Clinical case of metachronous ovarian metastases from colon cancer - observation of a clinical case and review of the literature
DOI:
https://doi.org/10.5281/zenodo.14860847Keywords:
ovarian metastasis, adnexectomy, colorectal cancer (CRC)Abstract
The incidence of ovarian metastases from colorectal cancer is relatively low in the range of 3-14%, and metachronous metastases are even lower 1.3-2.4%. In most cases, they occur in old age, during menopause and 12 months after diagnosis with CRC, creating some diagnostic challanges.
We present a clinical case of a 78-year-old woman who underwent emergency surgery for colon adenocarcinoma. One year later, bilateral ovarian lesions and peritoneal carcinosis were found. The performed colonoscopy did not detect recurrent colon tumor. The patient underwent a hysterectomy with bilateral adnexectomy. The results of histological and immunohistochemical examination confirmed the origin of ovarian tumors.
References
1. Birnkrant A, Sampson J, Sugarbaker PH. Ovarian metastasis from colorectal cancer. Dis Colon Rectum. 1986 Nov; 29(11):767-71.
2. GodzeKir, AyseGurbuz, AtesKarateke A, Mustafa Kir. Clinicopathologic and immunohistochemical profile of ovarian metastases from colorectal carcinoma. World J GastrointestSurg 2010 Apr 27; 2 (4): 109-16. Doi 10.4240/wjgs.v2.i4.109.
3. Graffner HO, Alm PO, Oscarson JE. Prophylactic oophorectomy in colorectal carcinoma.Am J Surg. 1983 Aug; 146(2):233-5.
4. Khunamornpong S, Suprasert P, Chiangmai WN, Siriaunkgul S. Metastatic tumors to the ovaries: a study of 170 cases in northern Thailand. Int J Gynecol Cancer. 2006;16 Suppl 1:132–138.
5. Kim DD, Park IJ, Kim HC, et al. Ovarian metastases from colorectal cancer: A clinicopathological analysis of 103 patients. Colorectal Dis. 2009;11:32 -38.
6. Levis Michael R , Michael T Deavers, Elvio G Silva, Anais Malpica . Ovarian involvement by metastatic colorectal adenocarcinoma: still a diagnostic challenge. Am J SurgPathol. 2006 Feb.; 30 (2):177-84. DOI: 10.1097/01.pas.0000176436.26821.8a.
7. Moss E L, Hollingworth J, Reynolds T M. The role of CA125 in clinical practice.J Clin Pathol.2005 Mar; 58 (3):308-312.
8. Paramyothiotis D. Metachronous Ovarian Metastases in a Patient with Primary Colorectal Cancer. A Case Report and Review of the Literature.Am J Case Rep. 2019; 20:1515-1520.
9. Rosen DG, Wang L, Atkinson JN, Yu Y, Lu KH, Diamandis EP, et al. Potential markers that complement expression of CA125 in epithelial ovarian cancer. Gynecol Oncol. 2005; 99:267–77.
10. Sakakura C, Hagiwara A, Yamazaki J, et al. Management of postoperative follow-up and surgicaltreatment for Krukenberg tumor from colorectal cancers. Hepatogastroenterology. 2004;51:1350–53.
11. Segelman J, Floter-Radestad A, Hellborg H, et al. Epidemiology and prognosis of ovarian metastases in colorectal cancer. Br J Surg. 2010;97:1704–9.
12. Vasu Reddy Challa,Y.G.Basavana Goud, Poornima Rangappa,Vijayalakshmi Deshmane, K. V. Veerendra Kumar, and B. A. Madhusudhana“Ovarian Metastases from Colorectal Cancer: Our Experience”. Indian J Surg Oncol. 2015 Jun; 6(2): 95–98.
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Copyright (c) 2023 Anna Taseva, V. Ivanova, Elena Arabadzhieva, Atanas Yonkov (Author)
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