The diagnostic role of ultrasoundguided needle biopsy in patients with peripherally located masses of the thorax, mediastinum and chest wall
DOI:
https://doi.org/10.5281/zenodo.14863188Keywords:
Ultrasound-guided needle biopsy, lung lesions, ultrasound, CTAbstract
Introduction: Worldwide, lung cancer is the most common cause of death from malignancy in both men and women. Ultrasound-controlled transthoracic true-cut needle biopsy [UTTCNB] provides an opportunity for early diagnosis by histologic verification of peripheral tumor masses in the lung, mediastinum, and chest wall evaluated as neoplasia by the imaging tests.
The aim: Оf the study was to estimate the sensitivity and specificity of the procedure.
Material and methods: A total of 264 patients underwent verification with UTTCNB between January 2020 and December 2021.
Results: Our analysis showed a high diagnostic reliability of UTTCNBfor pulmonary lesions - 93% (AUC = 0.930, p < 0.001), with a sensitivity of 90% and a specificity of 95.83%. Positive predictive value (PPV) is 90% and negative predictive value (NPV) is 95.80%The method is also associated with high sensitivity for lesions of the chest wall and mediastinum.
Conclusions: UTTCNB appears to be a safe, cost-effective and accurate method of biopsy diagnosis, devoid of radiation burden, applicable to various peripheral lesions in the chest area, allowing real-time control of the interventional procedure. It should be established as a method of first choice in patients with pulmonary lesions accessible to ultrasound imaging, those of the chest wall and mediastinum.
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Copyright (c) 2023 Dimcho Argirov, B. Yavorov, V. Aleksiev, F. Shterev, S. Kartev, A. Chapkanov, Z. Vazhev (Author)
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